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Schematic representation of schistosome DNA vaccine constructs. DNA sequences encoding the antigens were cloned into the pVAX1 plasmid at the indicated restriction sites. In case of the Hsp70-fusion constructs, antigens were spaced from Hsp70 by two codons for the amino acids (Glycine-Serine) which were generated by the BamHI site used to join both sequences.
