Fig. 2.

Newborn genotype at the FLT1 locus differs according to maternal parity and season of birth. (A) Frequency distribution of FLT1 3′ UTR repeat lengths, with S and L allele classification shown on graph as black and white bars, respectively. Relative proportion of flanking SNP variants, for individuals homozygous for specific repeat lengths with the reference allele (i.e., allele most common in Caucasians), is shown as black in boxes below graph. (B) Genotypes of mothers and their newborns, shown as proportions stratified by parity. (C) Genotypes of newborns according to season of birth, shown as proportions stratified by maternal parity. The proportions of SS and LL homozygotes are represented in black and white, respectively, with the SL heterozygotes in a hatched pattern. P values were calculated by using χ² test (2 × 3) across all genotypes. P1, nulliparous pregnancy; P≥3, multiparous pregnancy.