Table 1.
(ΔF/F)peak |
FDHM, ms |
|||||||
---|---|---|---|---|---|---|---|---|
T | Z | M | Global | T | Z | M | Global | |
Control | 2.01 ± 0.03 (200/10) | 1.29 ± 0.04 (98/10) | 1.33 ± 0.03 (98/10) | 1.82 ± 0.10 (11/7) | 2.13 ± 0.02 (200/10) | 2.62 ± 0.06 (98/10) | 2.57 ± 0.06 (98/10) | 2.24 ± 0.07 (9/7) |
mdx | 1.50 ± 0.02 (140/11) | 0.92 ± 0.03 (70/11) | 1.05 ± 0.02 (73/11) | 1.37 ± 0.07 (11/9) | 2.33 ± 0.03 (140/11) | 3.18 ± 0.13 (70/11) | 2.93 ± 0.08 (73/11) | 2.35 ± 0.13 (9/9) |
Percentage change | −25* | −29* | −21* | −25* | +9.6* | +22* | +14* | +4.9 |
Values are expressed as mean ± SEM. (ΔF/F)peak and FDHM are the amplitude and the FDHM of ΔF/F transients, respectively. T, Z, and M denote confocal transients recorded at specific locations, and ″global″ denotes transients recorded with global illumination (see text). Percentage change is the decrease (−) or increase (+) of parameter values measured in mdx with respect to those measured in control fibers. The asterisk indicates statistically significant changes (P < 0.05). Numbers in parenthesis (n/f) are the number of records, n, and fibers, f. Data were obtained from seven mdx and nine control animals.