Fig. 4.

Number of secreted vesicle per μm².s (= j_v × 1μm/s₀) as a function of the rate of coatomer desorption from the membrane k_off. The transition to vesiculation is discontinuous, and is characterized by an hysteretic cycle (arrows), with high and low turnover thresholds. The parameters are the same as those used for Figs. 2 and 3.