. 2008 Sep 19;105(39):15028–15033. doi: 10.1073/pnas.0806619105

Table 1.

Homozygous spin mice with mutations in MyD88 are protected from foot inflammation

Genotype	No. mice with inflamed feet/no. total mice	P value^* vs. Ptpn6^spin/spin	P value^* vs. Ptpn6^spin/spin Myd88^poc/poc
Ptpn6^spin/spin	35/43	–	<0.0001
Ptpn6^spin/spin Myd88^poc/poc	0/27	<0.0001	–
Ptpn6^spin/spin Tnf^−/−	7/9	1	<0.0001
Ptpn6^spin/spin Stat1^{m1Btlr/m1Btlr}	2/2	1	0.0025
Ptpn6^spin/spin Ticam1^Lps2/Lps2	1/2	0.3636	0.0690
Ptpn6^spin/spin Irak4^{otiose/otiose}	0/2	0.0454	1

Mice were scored between the ages of 6 and 25 weeks for inflammatory lesions on the feet.

*Fisher's exact test, two-tail P value.