Table 2.
Genotypic and allelic distributions of I/D polymorphism of ADRA2B gene among the groups.
| Genotypes | Group 1 (70) | Group 2 (65) | Group 3 (75) |
|---|---|---|---|
| n (%) | n (%) | n (%) | |
| II | 6 (8.57) | 7 (10.77) | 18 (24.00) |
| ID | 34 (48.57) | 28 (43.08) | 35 (46.67) |
| DD | 30 (42.86) | 30 (46.15) | 22 (29.33) |
| Significance | 0.029* | 0.046* | - |
| Alleles I | 46 (32.86) | 42 (32.31) | 71 (47.33) |
| D | 94 (67.14) | 88 (67.69) | 79 (52.67) |
| Significance | 0.012* | 0.011* | - |
| Odds Ratio 95% CI | 0.545 (0.388-0.837) | 0.531 (0.326-0.595) | - |
* P value < 0.05 vs. group 3, obtained through Chi-square test