Table 1.
Patient 1 (16 yr)
|
Patient 2 (14.5 yr)
|
Patient 3 (15 yr)
|
||||
---|---|---|---|---|---|---|
Basal | pACTH | Basal | pACTH | Basal | pACTH | |
Cortisol (μg/dl) | 7 | 7.6 | 8.15 | 10.6 | 7.9 | 8.16 |
17OHP (μg/liter ) | 7.73 (<2) | 16.35 | 5.59 (<2) | 19.35 | 13.80 (<2) | 15.50 |
DHEA-S (μg/dl) | 95 (80−560) | 72 (80−560) | 90 (80−560) | |||
Testosterone (ng/dl) | 100 (245−1200) | 110 (245−1200) | 200 (245−1200) | |||
FSH (mIU/ml) | 4.8 | 19 | 8 | |||
LH (mIU/ml) | 6.6 | 2.4 | 11 | |||
ACTH (pmol/liter) | 15 (1−10) | 8.3 (1−10) |
Age-appropriate normal ranges are given in parentheses for the patients. These values were obtained when the patients were not receiving testosterone replacement therapy. The columns pACTH designate steroid hormone values in response to 0.25 mg of ACTH. Conversion factors for SI units are as follows: to convert cortisol to nmol/liter, multiply by 27.6; to convert DHEA-S to μmol/liter, multiply by 0.0271; to convert 17OHP to nmol/liter, multiply by 3.03; and to convert testosterone to nmol/liter, multiply by 0.0347.