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Reciprocal changes in apparent dissociation constants: Kd (antagonist bound)/Kd (control)
| TPrA (toxin antagonist) | Toxin (TPrA antagonist) | DEA (toxin antagonist) | Toxin (DEA antagonist) | |
|---|---|---|---|---|
| R13E | 1.10 | 1.04 | 1.51 | 1.48 |
| R13Q | 1.14 | 1.07 | 1.44 | 1.51 |
Values were calculated assuming microscopic reversibility and steady state among the four possible occupancy states (Fig. 10).
