Table 3.

Association of Cyclin D1 870 G>A (rs603965) Polymorphism and Family History of Colorectal Cancer in Endometrial Cancer Cases

Genotype	FH of Colorectal Cancer in Endometrial Cancer Cases (n = 191)		χ2	OR (95% CI) and p value
	Yes n (%)	No n (%)
GG	6 (3.1)	43 (22.5)	p = 0.084	1.00 (reference)
GA	16 (8.4)	78 (40.8)		1.470 (0.536–4.034)	p = 0.454
AA	14 (7.3)	34 (17.8)		2.951 (1.026–8.491)	p = 0.045
GA+AA	30 (15.7)	112 (58.6)	p = 0.170#	1.920 (0.747–4.936)	p = 0.176
GG+GA	22 (11.5)	121 (63.4)	p = 0.035†	2.265 (1.048–4.894)	p = 0.038

Note: FH, family history.

# p value: Wild type genotype (GG) compared to combination of heterozygous and homozygous variant genotypes (GA+AA).

† p value: Homozygous variant genotype (AA) compared to combination of wild type and heterozygous genotypes (GG+GA).