Table 5.
Correlation of S100A3 mRNA expression with clinicalpathological parameters in patients with gastric carcinoma.
| Variable | mRNA expression | P | ||||
| Number | N/T >4 | N/T 2–4 | N/T 1–2 | N/T <1 | ||
| Gender | ||||||
| Male | 61 | 11 | 34 | 9 | 8 | 0.17 |
| Female | 19 | 3 | 5 | 8 | 2 | |
| Age (y) | ||||||
| <65 | 54 | 10 | 31 | 6 | 7 | 0.08 |
| >65 | 26 | 4 | 8 | 11 | 3 | |
| Tumor differentiation | ||||||
| Well1 | 3 | 0 | 0 | 1 | 2 | 0.22a |
| Moderate2 | 33 | 8 | 7 | 12 | 6 | 0.03b |
| Poor3 | 44 | 6 | 32 | 4 | 2 | 0.01c |
| Tumor size (cm) | ||||||
| <5.0 | 41 | 6 | 23 | 5 | 7 | 0.96 |
| >5.0 | 39 | 8 | 16 | 12 | 3 | |
| Depth of wall invasion | ||||||
| Mucosa, submucosa1 | 6 | 2 | 1 | 2 | 1 | 0.45a |
| Muscularis propria2 | 18 | 6 | 8 | 4 | 0 | 0.33b |
| Subserosa, serosa3 | 56 | 10 | 34 | 6 | 6 | 0.72c |
| Stage | ||||||
| I + II | 19 | 2 | 7 | 5 | 5 | 0.04 |
| III + IV | 61 | 12 | 32 | 12 | 5 | |
| Microscopic subtypes | ||||||
| Intestinal1 | 57 | 10 | 29 | 11 | 7 | 0.87a |
| Diffuse2 | 18 | 4 | 8 | 4 | 2 | 0.26b |
| Atypical3 | 5 | 0 | 2 | 2 | 1 | 0.21c |
| Lymph node metastasis | ||||||
| Yes | 64 | 11 | 35 | 11 | 7 | 0.16 |
| No | 16 | 3 | 4 | 6 | 3 | |
aP: 1 VS 2; bP: 2 VS 3; cP: 1 VS 3.