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Strains lacking either Slf1p or Sro9p are less sensitive to a subset of protein synthesis inhibitors. Wild-type cells, slf1::HIS3 cells, sro9::URA3 cells, and slf1::HIS3 sro9::URA3 cells were plated on YPD agar in the presence of disks containing 2.5 mg paromomycin (A), 2.5 μg cycloheximide (B), 200 μg hygromycin B (C), or 100 μg anisomycin. Plates were incubated for 2 d at 24.5°C.
