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. 1982 Mar;41(3):1099–1104. doi: 10.1128/jvi.41.3.1099-1104.1982

Purification of glycoprotein gD of herpes simplex virus types 1 and 2 by use of monoclonal antibody.

R J Eisenberg, M Ponce de Leon, L Pereira, D Long, G H Cohen
PMCID: PMC256850  PMID: 6284965

Abstract

Glycoproteins gD-1 and gD-2 of herpes simplex virus types 1 and 2, respectively, were purified on an immunoadsorbent consisting of the type-common monoclonal antibody HD-1 linked to Sepharose. Each glycoprotein was of sufficient purity, quantity, and biological activity to be used for immunological and biochemical studies. Each glycoprotein induced high titers of type-common monospecific neutralizing antibody in mice. Amino aicd analysis indicated that gD-1 and gD-2 had similar though not identical amino acid compositions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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