Figure 6. Effect of the Ca²⁺ channel blocker Cd²⁺ on hypoosmotic medium-induced amino acid release in the cortex.

(a–c) Microdialysis probes were perfused with hypoosmotic medium (HYPO) in the presence or absence of 300 µM Cd²⁺ given 20 minutes prior to and during one-hour hypoosmotic medium perfusion. Each rat had two microdialysis probes implanted on opposite sides of the cortex (one perfused with HYPO alone and the other with HYPO+Cd²⁺). The data represent the average dialysate levels ±SEM of glutamate (a), aspartate (b), and taurine (c) from 5 rats.