Table 4.

Age-related changes in dispersion derivatives

Region	Right hand						Left hand
	Side	Talairach coordinates in MNI space			Z-value	Correlation analysis (r2)	Side	Talairach coordinates in MNI space			Z-value	Correlation analysis (r2)
		x	y	z				x	y	z
Increasing dispersion with increasing age2
Intraparietal sulcus	R	38	−62	38	4.80*	0.52	R	28	−72	48	4.15	0.39
							L	−22	−72	50	4.17	0.43
Cerebellum (lobule VI)							R	40	−48	−28	4.99*	0.57
							L	−48	−56	−28	4.98*	0.55
Decreasing dispersion with increasing age2
None

Voxels in which there is a correlation between the parameter estimate for the temporal (B_T) or dispersion (B_D) derivative of the haemodynamic response function during hand grip and age². All peak voxels are significant at a height threshold of P < 0.001, uncorrected, and extent (cluster) threshold of P < 0.05, corrected for multiple comparisons across whole brain. Voxels marked ‘*’ are significant at a height threshold of P < 0.05, corrected for multiple comparisons across whole brain. Cerebellar localization performed from Schmahmann et al. (1999).