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. 2008 Oct 31;4(10):e1000193. doi: 10.1371/journal.ppat.1000193

Figure 5. Kinetics of IFN-β priming.

Figure 5

(A,B) cDCs were pretreated with IFN-β (50 units/ml) for 24, 12, 6, 3, 1, and 0.5 hours prior to 12-hour infection with PR8 virus in fresh media. (C,D) pDCs were pretreated with IFN-β (50 units/ml) for 24, 12, 6, 3, 1, and 0.5 hours prior to 4-hour infection with PR8 virus in fresh media. Control DCs have only PR8 virus infection (PR8) or IFN pretreatment (IFN) or neither (NI). (A,C) Copy number of mRNA expression values are depicted for the specific gene labeled. (B,D) Protein secretion amounts from multiplex ELISAs. Mean of samples are depicted with error bars of the standard deviation of each sample. Data are representative of at least three independent experiments. Samples with student t test p<0.05 between the IFN+PR8 condition, and the other conditions are marked with *.