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. 2008 Oct 27;3(10):e3518. doi: 10.1371/journal.pone.0003518

Figure 2. Plasma membrane, cytoplasm and nucleus addressing of TRAF4 deletion mutants.

Figure 2

Left part: Schematic representation of the 3 constructs coupled to Flag. A: full-length TRAF4 (AA1-470), B (AA1-281) and C (AA282-470). Right part of the figure represents image projection of several confocal sections. Mutant C containing the TRAF domain only was addressed to the plasma membrane and nucleus, like the full-length TRAF4 protein, but was absent from the cytoplasm. In contrast, mutant B devoid of the TRAF domain was only addressed to the cytoplasm. AA: amino acid.