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. 2008 May 21;116(10):1294–1299. doi: 10.1289/ehp.11021

Figure 5.

Figure 5

(A) Relaxant effect of ACh in rat intrapulmonary arteries incubated for 24 hr in the absence (control) or presence of dexamethasone (10 μM), SRM1648 (200 μg/mL), or SRM1648 (200 μg/mL) plus dexamethasone (10 μM). Data are mean ± SE from 4 or 5 rats. (B) TNF-α and MIP2 release from rat intrapulmonary arteries incubated for 24 hr in the absence (white bars) or presence (black bars) of SRM1648 (200 μg/mL). Data are mean ± SE from 9–10 rats. (C) IL-8 release from bovine intrapulmonary artery endothelial cells incubated for 24 hr in the absence (white bar) or presence (black bar) of SRM1648 (200 μg/mL). Data are mean ± SE from three or four experiments. NS, not significant. *p < 0.05; **p < 0.01.