Table 1. Non-linear model fits for associations with estimated age at diagnosis.
| Variable | n | Adj R2 | p Value | Non-linear df | Non-linear p value |
| Motor examination score | 438 | 0.15 | <0.0001 | 3 | <0.0001 |
| Striatal volume | 261 | 0.23 | <0.0001 | 1 | <0.001 |
| Speeded finger tapping rate (mean) | 408 | 0.14 | <0.0001 | 3 | <0.0001 |
| Consistency in self-timed finger tapping | 410 | 0.20 | <0.0001 | 3 | <0.0001 |
| Word list learning (HVLT) | 425 | 0.09 | <0.0001 | 1 | <0.01 |
| Odour identification | 424 | 0.10 | <0.0001 | 1 | <0.0001 |
Adj R2 = partial adjusted variance accounted for by estimated years to diagnosis to Huntington’s disease (HD) after accounting for covariates (see statistical methods section) and degrees of freedom used for non-linear fit.
HVLT, Hopkins Verbal Learning Test; Non-linear df, degrees of freedom for non-linear fit; non-linear p value, p value for non-linear element of estimated years to HD diagnosis fit.