Table 3.

Significant clusters of activation during direct comparison of Happy vs Sad chimeric faces (paired t-test) separately for left-lateralized and right-lateralized affective presentations.

Regions of activation	Active voxels	x	y	z	z-score
Left visual field affect
Happy > sad
—	—	—	—	—	—
Sad > happy
R. Insula	270	42	6	−16	3.97
L. Insula	105	−40	14	−6	3.59
R. Anterior cingulate gyrus	124	8	30	18	3.49
L. Middle occipital gyrus	71	−20	−86	18	3.32
L. Fusiform gyrus	140	−36	−6	−28	3.30
R. Lingual gyrus	69	10	−60	−4	3.29
R. Posterior cingulate gyrus	25	10	−44	14	3.21
L. Middle frontal gyrus	49	−34	48	0	3.15
R. Post-central gyrus	33	28	−34	56	3.09
R. Inferior temporal gyrus	31	46	−18	−22	3.08
L. Anterior cingulate gyrus	23	−2	32	16	3.00
L. Supramarginal gyrus	53	−62	−32	36	2.98
R. Middle cingulate gyrus	22	20	−6	44	2.97
R. Middle frontal gyrus	32	44	8	40	2.78
Right Visual field affect
Happy > sad
L. Middle temporal gyrus	110	−52	−38	−10	3.20
R. Middle temporal gyrus	29	48	−74	16	2.95
Sad > happy
R. Insula	199	42	8	−16	3.66
L. Insula	94	−40	14	−6	3.45
L. Superior frontal gyrus	60	−30	48	0	3.23
R. Middle frontal gyrus	28	32	8	52	3.23
R. Lingual gyrus	27	10	−60	−4	3.22
L. Fusiform gyrus	77	−32	−2	−40	3.14
R. Inferior orbital frontal gyrus	24	48	28	−6	2.88

Note: L, left hemisphere; R, right hemisphere; LVF, left visual field; RVF, right visual field. Atlas coordinates are from the MNI standard atlas, such that x reflects the distance (mm) to the right or left of midline, y reflects the distance anterior or posterior to the anterior commissure and z reflects the distance superior or inferior to the horizontal plane through the AC-PC line. P < 0.005 (uncorrected), k = 20 voxels.