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(A) Alignment of amino acid sequences of the human Hint1 and Hint2. Amino acids conserved between both sequences are indicated in blue, and the 3 histidines of the HIT motif are indicated in red. (B) Phylogenic tree established by comparison of interspecies sequences of Hint1, Hint2, and Hint3 proteins using ClustalW software (http://www.ebi.ac.uk/clustalw/).
