Table 2.
The body weight of offspring (LS mean ± SEM) by age with the number of animals in each condition underneath. P21 was chosen to show body weights shortly after the end of treatment. P35 was chosen to show body weight a week after weaning. P56 was chosen to show body weight shortly before the start of behavioral testing. P91 was chosen to show body weight after the conclusion of behavioral testing
| Group | |||||
|---|---|---|---|---|---|
| Age (P) | Saline | MA-10 | MA-15 | MA-20 | MA-25 |
| Males | |||||
| 21 | 61.6 ± 1.8 36† |
50.0 ± 1.8* 34 |
47.2 ± 1.8* 34 |
45.5 ± 1.8* 33 |
44.4 ± 1.9* 30 |
| 35 | 170.7 ± 4.8 38 |
156.4 ± 4.9* 36 |
150.3 ± 5.0* 34 |
146.5 ± 4.9 35 |
145.1 ± 5.3* 30 |
| 56 | 370.1 ± 4.8 36 |
356.7 ± 4.9* 34 |
347.3 ± 5.1* 31 |
336.8 ± 4.9* 33 |
347.3 ± 5.4* 27 |
| 91 | 522.7 ± 4.9 32 |
513.4 ± 5.1* 30 |
491.3 ± 5.2* 29 |
484.7 ± 5.1* 30 |
492.9 ± 5.6* 24 |
| Females | |||||
| 21 | 57.7 ± 1.8 36 |
47.8 ± 1.8* 36 |
45.5 ± 1.8* 35 |
45.3 ± 1.8* 34 |
41.8 ± 1.9* 29 |
| 35 | 141.8 ± 4.8 38 |
134.0 ± 4.8 38 |
125.7 ± 4.9 36 |
130.7 ± 4.9 36 |
126.4 ± 5.3 30 |
| 56 | 241.1 ± 4.8 36 |
234.3 ± 4.8 36 |
226.8 ± 4.9 33 |
233.0 ± 4.9 33 |
228.2 ± 5.2 29 |
| 91 | 301.8 ± 4.9 32 |
295.8 ± 4.9 32 |
295.3 ± 5.1 29 |
299.9 ± 5.1 29 |
299.3 ± 5.4 26 |
*
P < 0.001 compared to Saline for all ages in males and on P21 and P28 only for females.
†
N = group size.