Table I.
Comparison of different parameters analysed for lesion establishment and appearance in control mice and TM-stimulated mice (n = 20 per group).
| Parameter | Control | TM-group | P-value |
|---|---|---|---|
| Mice with no lesions | 1 (5%) | 5 (25%) | |
| Mice with debris | 8 (40%) | 18 (90%) | |
| Mean lesion number per mouse | 2.40 ± 1.4 | 1.65 ± 1.4 | |
| Lesion number range | 0–6 | 0–4 | |
| Mean of CSA/mouse (mm2) | 4.86 ± 4.52 | 1.41 ± 1.63 | |
| Median of CSA (mm2) | 1.60 ± 5.99 | 0.60 ± 1.86 | |
| Geometric mean of CSA (mm2) | 1.33 ± 6.28 | 0.60 ± 3.48 | |
| Sum CSA of all lesions (mm2) | 217.43 | 44.18 | |
| Median of sum CSA (mm2) | 8.8 ± 9.93 | 0.92 ± 3.26 | 0.0013 |
Statistical analysis: F test (CSA), Wilcoxon rank-sum test (Sum CSA). CSAs, cross-sectional areas.