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. Author manuscript; available in PMC: 2008 Oct 17.
Published in final edited form as: Annu Rev Biochem. 2001 Nov 9;71:635–700. doi: 10.1146/annurev.biochem.71.110601.135414

Figure 10. Structure of lipooligosaccharides from Neisseria meningitidis.

Figure 10

The structures and immunotypes have been reviewed elsewhere (168, 246). The structure of the single α-chain in each LOS varies and shown here are the sialylated α-chains from immunotypes L1 (374) and L3. Some of the additions to the inner core are missing in some LOS species. Relevant glycosyltransferases involved in the synthesis are identified, and the basis for the structural variations is described in the text. The RfaK enzyme should not be confused with the WaaK (formerly RfaK) glycosyltransferases that adds the terminal GlcNAc residue to the outer core of S. enterica serovar Typhimurium LPS.