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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Ultrasonics. 2008 Apr 14;48(4):279–296. doi: 10.1016/j.ultras.2008.04.004

FIGURE 5.

FIGURE 5

Possible mechanisms for blood-brain barrier disruption via ultrasound + microbubbles. Assuming that the effect is not due to bubble collapse (inertial cavitation), possible effects include stimulation of the endothelial cells via radiation force on the bubbles, bubble oscillation or from microstreaming of the fluid around the bubbles.