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. 2008 Oct 15;22(20):2823–2830. doi: 10.1101/gad.1698108

Figure 1.

Figure 1.

The core promoters of Drosophila Hox genes contain a conserved DPE motif. The core promoter sequences of the indicated D. melanogaster Hox genes are shown. We initially analyzed the sequence conservation of the promoters in eight different Drosophila species by using VISTA tools and CLUSTALW (Supplemental Fig. 1; data not shown). Based on this sequence alignment, positions that are identical between D. melanogaster and D. virilis (in terms of sequence and spacing relative to the A + 1 in the Inr) are shaded. D. melanogaster and D. virilis are estimated to be separated by an evolutionary period of ∼40–60 million years.