Table 3.
Univariable Cox proportional hazards model predicting the combined primary endpoint myocardial infarction and cardiac death (MI and CD) in dependence of cardiovascular risk factors and Agatston scores above the 75. percentile
| relative risk | 95% CI | p value | |
| no risk factors | 1 | - | - |
| arterial hypertension | 2.47 * | 2.21–2.81 | 0.005 |
| smoking | 2.14 * | 2.01–2.33 | 0.005 |
| hyperlipidemia | 2.75 * | 2.49–3.19 | 0.006 |
| microalbuminuria | 1.36 | 1.30–1.47 | 0.151 |
| proteinuria | 1.71 * | 1.56–1.97 | 0.018 |
| familiy history | 1.45 * | 1.28–1.73 | 0.012 |
| duration of diabetes | 1.51 | 1.39–1.69 | 0.013 |
| retinopathy | 1.76 * | 1.60–2.04 | 0.013 |
| HbA1C | 1.89 * | 1.69–2.19 | 0.009 |
| Framingham risk score | 6.0 * | 4.9–7.8 | 0.004 |
| UKPDS Score | 7.1 * | 6.0–8.9 | 0.003 |
| Agatston score > 400 | 14.2 * | 12.7–16.8 | 0.001 |
* indicates a significant difference (p < 0.05) compared to the patient group without cardiovascular risk factors and without coronary calcifications, respectively.