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. Author manuscript; available in PMC: 2008 Oct 20.
Published in final edited form as: Cancer Res. 2007 Mar;67(6):2552–2558. doi: 10.1158/0008-5472.CAN-06-3870

Figure 5.

Figure 5

Interaction of liprin α1 and ING4 on regulating cell motility. A, Endogenous liprin α1 in RKO cells transfected with control vector (Cont) and two siRNAs (Lip-KDl and Lip-KD2) was detected by chicken liprin α1 antibody. RKO cells transfected with the control vector, pcDNA-ING4, the two liprin α1 siRNAs with/without ING4 for 72 h were used for the cell spreading assay. After 1 h serum stimulation, the ratio of cells with filo/lamellipodia was calculated. * Indicates p<0.0001 compare with the control (Student’s t-test). B, RKO cells transfected with the same vector and/or siRNAs used for A were subjected to a modified Boyden chamber assay. * Indicates p<0.002 compared with the control (Student’s t-test).