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The effect of K14-driven mIGF-1 expression on the hair coat. A and B: Awl and guard hair shafts are shown. C: Transgenic guard hairs (g) are elongated by 20% (***P > 0.0001), transgenic awl hairs (a) are elongated by 10% (***P > 0.001), whereas zigzag hair (z) length is not changed. D: The frequencies of zigzag (z) and awl (a) hairs in wild-type mice are 79% and 21%, respectively, and in transgenic mice they are 60% and 40%, respectively.
