Table 2.
Disease Score
Score | Characterization | Clinical signs |
---|---|---|
0 | No clinical signs | — |
1 | Mild clinical signsa | Ruffled fur |
2 | Moderate clinical signs | Ruffled fur plus, lethargy, hunched posture, decreased activity |
3 | Severe clinical signs | Paresis, paralysis, tremor, shivers, ataxia, rigidity, coma |
4 | Death | — |
Mice that exhibited only mild clinical signs, did not show further signs of disease and recovered until the end of the experiment were not considered ill.