Table 2.
Table Showing Fifty-Eight Differentially Expressed Genes Specific for Dysferlin Deficient Group with their Respective P Value and Fold Change from PLIER
| Probe set | P value | Fold change | Gene Symbol | Description |
|---|---|---|---|---|
| 233696_at* | <0.001 | −1.97 | VPS37C | Vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| 210251_s_at | <0.001 | 2.91 | RUFY3 | RUN and FYVE domain containing 3 |
| 213457_at | <0.001 | 3.48 | MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1 |
| 211551_at | <0.001 | −2.29 | EGFR | Epidermal growth factor receptor |
| 227812_at | <0.001 | 3.17 | TNFRSF19 | Tumor necrosis factor receptor superfamily, member 19 |
| 205640_at | <0.001 | 6.86 | ALDH3B1 | Aldehyde dehydrogenase 3 family |
| 227798_at | <0.001 | 1.60 | SMAD1 | SMAD, mothers against DPP homolog 1 (Drosophila) |
| 219517_at | <0.001 | 2.66 | ELL3 | Elongation factor RNA polymerase II-like 3 |
| 209515_s_at | <0.001 | 3.06 | RAB27A | RAB27A, member RAS oncogene family |
| 36030_at | <0.001 | 2.11 | HOM-TES-103 | Hypothetical protein LOC25900 |
| 209211_at | <0.001 | 3.00 | KLF5 | Kruppel-like factor 5 (intestinal) |
| 216609_at | <0.001 | 3.20 | TXN | Thioredoxin |
| 200772_x_at | <0.001 | 2.04 | PTMA | Prothymosin, alpha (gene sequence 28) |
| 204736_s_at | <0.001 | 4.08 | CSPG4 | Chondroitin sulfate proteoglycan 4 |
| 209212_s_at | <0.001 | 2.42 | KLF5 | Kruppel-like factor 5 (intestinal) |
| 218691_s_at | <0.001 | 3.39 | PDLIM4 | PDZ and LIM domain 4 |
| 216294_s_at | <0.001 | −2.21 | KIAA1109 | KIAA1109 |
| 222288_at | <0.001 | 3.20 | NK | Transcribed locus |
| 211921_x_at | 0.001 | 2.15 | PTMA | Prothymosin, alpha (gene sequence 28) |
| 209360_s_at | 0.001 | 4.34 | RUNX1 | Runt-related transcription factor 1 (acute myeloid leukemia 1) |
| 1552263_at | 0.001 | 2.76 | MAPK1 | Mitogen-activated protein kinase 1 |
| 225188_at | 0.001 | 2.42 | RAPH1 | Ras association and pleckstrin homology domains 1 |
| 203186_s_at | 0.001 | 2.26 | S100A4 | S100 calcium binding protein A4 |
| 221765_at | 0.001 | 3.44 | UGCG | UDP-glucose ceramide glucosyltransferase |
| 216791_at | 0.001 | −1.77 | TMEM92 | Transmembrane protein 92 |
| 225852_at | 0.001 | 1.48 | ANKRD17 | Ankyrin repeat domain 17 |
| 205478_at | 0.001 | −2.59 | PPP1R1A | Protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| 223538_at | 0.001 | 1.65 | SERF1A | Small EDRK-rich factor 1A (telomeric) |
| 212295_s_at | 0.001 | 2.04 | SLC7A1 | Solute carrier family 7, member 1 |
| 227253_at | 0.001 | 2.84 | CP; HPS3 | Ceruloplasmin (ferroxidase) |
| 238013_at | 0.001 | 4.11 | PLEKHA2 | Pleckstrin homology domain containing |
| 209169_at | 0.001 | 2.66 | GPM6B | Glycoprotein M6B; |
| 235981_at | 0.001 | −3.03 | C8orf22 | Chromosome 8 open reading frame 22 |
| 211503_s_at | 0.001 | 1.52 | RAB14 | RAB14, member RAS oncogene family |
| 225496_s_at | 0.001 | 2.99 | SYTL2/Slp2a | Synaptotagmin-like 2; synonyms: SLP2, |
| 238909_at | 0.001 | 2.04 | S100A10 | S100 calcium binding protein A10 |
| 201645_at | 0.001 | 6.41 | TNC | Tenascin C (hexabrachion) |
| 1554513_s_at | 0.002 | 1.47 | CCDC123 | Coiled-coil domain containing 123 |
| 206714_at | 0.002 | −1.73 | ALOX15B | Arachidonate 15-lipoxygenase, type B |
| 225189_s_at | 0.002 | 2.16 | RAPH1 | Ras association and pleckstrin homology domains 1 |
| 204619_s_at | 0.003 | 2.64 | CSPG2 | Chondroitin sulfate proteoglycan 2 (versican) |
| 222876_s_at | 0.003 | 2.33 | CENTA2 | Centaurin, alpha 2 |
| 211862_x_at | 0.003 | −1.56 | CFLAR | CASP8 and FADD-like apoptosis regulator |
| 243794_at | 0.003 | −2.13 | NK | Transcribed locus |
| 224563_at | 0.003 | 2.96 | WASF2 | WAS protein family, member 2 |
| 236304_at | 0.003 | 2.70 | NK | Transcribed locus |
| 217040_x_at | 0.003 | −1.76 | SOX15 | SRY (sex determining region Y)-box 15 |
| 201291_s_at | 0.003 | 4.28 | TOP2A | Topoisomerase (DNA) II alpha 170kDa |
| 217728_at | 0.003 | 2.11 | S100A6 | S100 calcium binding protein A6 |
| 208485_x_at | 0.003 | −1.57 | CFLAR | CASP8 and FADD-like apoptosis regulator |
| 231712_at | 0.003 | 2.41 | NK | Transcribed locus, strongly similar to XP_525018.1 |
| 227595_at | 0.003 | 1.45 | ZMYM6 | zinc finger, MYM-type 6 |
| 225997_at | 0.004 | 1.88 | MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) |
| 232914_s_at | 0.004 | 2.33 | SYTL2/Slp2a | Synaptotagmin-like 2; synonyms: SLP2, |
| 206460_at | 0.004 | −2.30 | AJAP1 | Adherens junction associated protein 1 |
| 1552455_at | 0.004 | 2.74 | C9orf65 | Chromosome 9 open reading frame 65 |
| 227568_at | 0.004 | 2.00 | HECTD2 | HECT domain containing 2 |
| 222834_s_at | 0.005 | 2.04 | GNG12 | Guanine nucleotide binding protein (G protein), gamma 12 |
*
This probe corresponds to one of the small EST in VPS37C gene, NK, Not known.