i.t. |
R strain albino |
3 |
Antimicrobial therapy, model description |
CFU, histology |
Pathogenesis of lobar pneumonia, drug efficacy studies |
14 |
i.t. |
Sprague-Dawley |
3 |
Model in cirrhotic and chronically intoxicated rats |
Survival, CFU, hematology and chemistry tests |
Pneumonia in alcoholic and cirrhotic patients |
71, 166
|
Intrabronchial |
Wistar |
3 |
Effect of pneumolysin on lungs |
Lung histology |
Pathogenesis of lobar pneumonia, detailed surgery information |
79 |
Intrabronchial |
Infant CD |
6 |
Model of penicillin-resistant pneumonia in neutropenic rats |
Gross pathology and CFU |
Drug efficacy studies |
221 |
Intrapulmonary |
CD |
2, 6B |
Model of penicillin-resistant pneumonia in neutropenic rats |
CFU, lung histology, pharmacokinetics |
Antibiotic efficacy studies |
49 |
Intrapulmonary |
Infant Sprague-Dawley |
1, 3, 4, 5, 6B, 7F, 9V, 14, 19F, 23F |
Low-dose pneumonia model |
Survival, CFU, lung histology |
Pathogenesis of pneumonia in children, vaccine studies |
214 |