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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Hepatology. 2008 Sep;48(3):889–897. doi: 10.1002/hep.22400

Figure 5.

Figure 5

DMSO induces IFN-γ and granzyme B expression in hepatic NK cells. Frequencies of hepatic NK cells expressing IFN-γ (A and B) and granzyme B (C and D) 24 h following treatment with DMSO in saline (0%), 3.5%, 5%, or 10%. The frequencies of IFN-γ+ and granzyme B+ NK cells were determined by gating on the NK (NK1.1+CD3-) cell population. Data shown are representative of two independent experiments. Values represent the mean ± SEM of 5 mice per group. (*) P < 0.05 versus all other groups. Also shown are representative flow cytometry data of IFN-γ (B) and granzyme B (D) expression by NK cells in mice treated with (0%) or 10% DMSO in saline.