TABLE 2.
Mutational Status of p53 Gene in Brain Tumor Cells
Brain Tumor Cell Line | p53 Status | Mutated Exon | Mutated Codon | Nucleotide Changes | Amino Acid Substitution |
---|---|---|---|---|---|
MGR3 | Wild-type | - | - | - | - |
UW28 | Wild-type | - | - | - | - |
UW281 | Wild-type | - | - | - | - |
UW78 | Wild-type | 4 | 36 | CCG→CCA | None |
MGR2 | Mutant | 8 | 273 | CGT→CAT | Arg→His |
MGR1 | Mutant | 5 | 155 | ACC→AAC | Thr→Asn |
UW228 | Mutant | 5 | 155 | ACC→AAC | Thr→Asn |