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. Author manuscript; available in PMC: 2008 Oct 20.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2868–2876. doi: 10.1167/iovs.06-0035

Figure 6.

Figure 6

Truncated rhodopsin accelerates photoreceptor degeneration in adult mice. (A) Spider graphs of ONL thickness measurements taken in 100-μm increments from the optic nerve head (ONH) to the ora serrata (ORS) in both the inferior and superior retina indicate in the P220 littermate animals that overall thickness was greatest in WT mice, followed by WTKO, and was thinnest in CTCWTKO animals. (B) Average ONL thickness plotted against age in WTKO and CTCWTKO mice. The ONL of S334ter+, rho+/− mice was significantly thinner in older animals (P110–P120 and P220–P230). Note that the x-axis is not to scale. *P < 0.005; **P < 0.001 (significant by two-tailed, unpaired t-test).