Differential binding of Pax5 to individual members of the VHS107 family. (A) Alignment of the VHS107 family members. Solid line box, Pax5 binding site; gray shaded box, oligos used in EMSAs; dashed boxes, Nla III sites; circles, CpG sites; black lines, RSS elements. The start of the coding region is indicated with +1. (B) Binding of Pax5 to individual Pax5 binding sites using double-stranded labeled oligos from the CD19, V1, V11 and V13 genes and nuclear extracts from 18.8 cells. (C) Supershift assays performed with anti-Pax5 antibody.