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. Author manuscript; available in PMC: 2008 Oct 20.
Published in final edited form as: Antioxid Redox Signal. 2005;7(3-4):508–514. doi: 10.1089/ars.2005.7.508

Table 1.

Protection Against Oxidative Cell Death by Bcl-2 Family Members

Cell/animal type Form of cell death References
T cells from bcl-2 transgenic mice γ radiation, H2O2, menadione 17, 48, 52
Burkitt's lymphoma cell line transfected with bcl-2 C6-ceramide, TNF-α, resulting in cellular oxidative stress 12
Saccharomyces cerevisiae expressing bcl-2, ced-9, or bcl-xl Menadione, H2O2 6
SY5Y neuroblastoma cell line overexpressing Bcl-xL H2O2 30
T cells transfected with bcl-2 tert-Butyl hydroperoxide 59
GT1-7 and PC12 cell lines overexpressing Bcl-2 Glutathione depletion, menadione, tert-butyl hydroperoxide, cyanide/aglycemia 21, 40, 61
HeLa, MCF-7, and mouse lymphoma cell lines overexpressing Bcl-2 Glutathione depletion, γ radiation 35, 36, 46

TNF-α, tumor necrosis factor-α.