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. 2008 Nov;57(11):2933–2942. doi: 10.2337/db08-0349

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Copyright © 2008, American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — Mitochondrial ATP production rates. An age-related decline in mitochondrial ATP production was observed using substrates glutamate plus malate (GM) (A), succinate plus rotenone (SR) (B), and palmitoyl-l-carnitine plus malate (PCM) (C) in sedentary subjects. These effects of age were not apparent in endurance-trained subjects. Data are presented as means ± SEM. *Pairwise comparisons revealed significant (P < 0.05) effects of age within activity groups; **significant (P < 0.05) main effects of training. ▪, young; □, older.