Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Nov;57(11):3090–3098. doi: 10.2337/db08-0564

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2008, American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

PMC Copyright notice

FIG. 4. — Inhibition of TLR2 and TLR4 receptors using siRNA ameliorates high-glucose–induced NF-κB p65-dependent DNA binding activity in the nuclear extracts of THP-1 cells by ELISA as described in research design and methods. Values are normalized to milligrams nuclear protein and expressed as means ± SD. *P < 0.05 vs. Sc + high glucose (HG); Sc, scramble control siRNA; TLR2si, TLR2 receptor siRNA; TLR4si, TLR4 receptor siRNA. n = 4 experiments in duplicate. □, Mannitol; , LG (5.5 mmol/l); ▪, HG (15 mmol/l).

Inline graphic — Inhibition of TLR2 and TLR4 receptors using siRNA ameliorates high-glucose–induced NF-κB p65-dependent DNA binding activity in the nuclear extracts of THP-1 cells by ELISA as described in research design and methods. Values are normalized to milligrams nuclear protein and expressed as means ± SD. *P < 0.05 vs. Sc + high glucose (HG); Sc, scramble control siRNA; TLR2si, TLR2 receptor siRNA; TLR4si, TLR4 receptor siRNA. n = 4 experiments in duplicate. □, Mannitol; , LG (5.5 mmol/l); ▪, HG (15 mmol/l).