Table 2.

Muscle and plasma metabolite enrichment data and metabolic fluxes obtained during the TCA cycle flux experiment

	Sedentary	Trained
Plasma [acetate], mM	0.63 ± 0.07	0.65 ± 0.03
Plasma [2-13C]acetate APE, %	85.4 ± 1.1	86.4 ± 1.0
Muscle C2-glutamate APE, %	1.31 ± 0.32	1.39 ± 0.18
Muscle C4-glutamate APE†, %	2.62 ± 0.64	2.80 ± 0.36
VTCA, nmol/g (muscle) per min	59.6 ± 4.9	91.7 ± 7.6*
VAC/VTCA, %	3.6 ± 0.9	3.4 ± 0.4

APE, atom percent excess.

*P < 0.05.

^†Calculated from C₂-glutamate assuming 5% anaplerosis.