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. 2008 Oct 30;3(10):e3574. doi: 10.1371/journal.pone.0003574

Figure 2. Complete genomic structure of miR-433-127 gene cluster.

Figure 2

Chromosomal localization of miR-433 and miR-127 primary transcripts. Genes for miR-433 and miR-127 are located on chromosome 12 on the positive strand. The green arrows represent the TIS of the two overlapping transcripts, and the red triangles and arrows represent the TTS sites. The navy and teal arrows indicate the location of RACE primers used to clone pri-miR-344 and pri-miR-127, respectively. The length for the miR-433 and miR-127 gene is 1,842 bp and 1,124 bp, respectively. The TIS of pri-miR-127 is located within the 3′-end of pri-miR-433 and the pri-miR-433 transcript contains the promoter region of the miR-127 gene. These two transcripts share an overlapping region with a length of 297nt. The distance between the two precursor coding regions for miR-433 and 127 is 1,007 bp.