Table 2. Comparison of the phenotypic poor metabolisers and extensive metabolisers.
|
Phenotype
|
|||
|---|---|---|---|
| Poor metabolisers (log OMP HI >1) | Extensive metabolisers (log OMP HI <1) | ||
| median (IQ range) n=12 | median (IQ range) n=19 | P-valuea | |
| IL-1α | 111.2 (17.7, 287.3) | 107.2 (20.8, 794.5) | 0.61 |
| IL-1β | 1.4 (0, 39.2) | 1.1 (0, 2.3) | 0.35 |
| IL-6 | 65.9 (12.0, 82.7) | 38.0 (13.4, 134.9) | 0.97 |
| TNF | 7.4 (3.8, 12.5) | 6.5 (4, 9.3) | 0.57 |
| TGF | 497.5 (338.8, 641.3) | 490 (440, 553) | 0.63 |
| CRP | 9.1 (2.3, 39.3) | 8.7 (2.0, 24.0) | 0.76 |
| Albumin | 46.9 (43.4, 50.2) | 44.8 (43.0, 48.9) | 0.41 |
| Growth hormone | 988.8 (222.5, 3075) | 955.7 (496.3, 4117.2) | 0.44 |
| BMI | 27.7 (21.7, 30.0) | 23.7 (22.0, 27.6) | 0.09 |
Median and interquartile (IQ) ranges are shown for levels of inflammatory cytokines, albumin concentration, growth hormone concentration and body mass index (BMI).
a
Mann–Whitney rank-sum test.