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. 2008 Sep 23;99(8):1290–1295. doi: 10.1038/sj.bjc.6604677

Table 2. Correlation of TROP2 overexpression with conventional clinicopathological parameters.

    TROP2 overexpression
 
    No Yes  
  Total patients (n) n (%) n (%) P-value
Sex (n=197)
 Male 111 51 (46) 60 (54) 0.68
 Female 86 37 (43) 49 (57)  
         
Age at diagnosis (n=197)
 <65 years 84 37 (44) 47 (56) 0.88
 ⩾65 years 113 51 (45) 62 (55)  
         
Differentiation (n=181)
 Well 24 17 (71) 7 (29) 0.01
 Moderate 84 38 (45) 46 (55)  
 Poor 73 26 (36) 47 (64)  
         
T stage (n=176)
 pT1 13 5 (38) 8 (62) 0.06
 pT2 52 27 (52) 25 (48)  
 pT3 80 36 (45) 44 (55)  
 pT4 31 7 (23) 24 (77)  
         
Lymph node status (n=176)
 No 65 34 (52) 31 (48) 0.04
 Yes 111 41 (37) 70 (63)  
         
Distant metastasis (n=142)
 No 117 56 (48) 61 (52) 0.14
 Yes 25 8 (32) 17 (68)  
         
Surgical margin (n=128)
 Negative 86 45 (52) 41 (48) 0.10
 Positive 42 16 (38) 26 (62)  
         
Stage (UICC) (n=180)
 IA 6 4 (67) 2 (33) 0.03
 IB 24 15 (63) 9 (37)  
 IIA 34 15 (44) 19 (56)  
 IIB 70 32 (46) 38 (54)  
 III 20 3 (15) 17 (85)  
 IV 26 9 (35) 17 (64)