Table 4.

The Levels of iNOS (μg /mg Protein) and cGMP (n mol /mg Protein) in the Heart Tissues of Studied Groups 4 Weeks After Induction of Diabetes (n=10 in Each Group)

Groups	Control	Diabetic	INS	E 300	I±E300
iNOS	169 ± 29	451 ± 106*	277 ± 64*■	356 #x00B1; 78*	231 ± 58■
cGMP	1.3 ± 0.4	3.6± 0.6*	2.6± 0.5*■	2.3±0.8*■	1.4 ± 0.4■

Results are mean ±SD.

Ins= Insulin, E=300: vitamin E 300mg, I+E300: insulin 1U sc +Vitamin E 300 mg, iNOS: inducible nitric oxide synthase, cGMP= cyclic guanosine monophosphate.

*Significant with control (P < 0.001);■ Significant with DM (P < 0.01).