. Author manuscript; available in PMC: 2008 Dec 4.

Published in final edited form as: Biochemistry. 2007 Nov 8;46(48):13819–13828. doi: 10.1021/bi701249q

Table 2.

Inhibition of GABA transamination as measured by a reduction in the rate of conversion of [U-¹⁴C]-α-KG to [U-¹⁴C]-Glu over 15 min.

[(R)-2 or (S)-2] (mM)	% α-KG converted to Glu/unit time
[(R)-2 or (S)-2] (mM)	(R)-2	(S)-2

0.000	6.79	6.79
0.050	6.97	7.28
0.250	3.89	7.00
0.500	1.87	7.23
1.000	0.97	6.74