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Tumor incidence and anatomic localization of tumors in TEC3KO mice. (A, B) A typical schwannoma is shown in a TEC3KO mouse. Note the gelatinous consistency of the tumor and its localization to the facial nerve lateral to the orbit. (C) Kaplan-Meier plot of tumor onset in a cohort of TEC3KO animals (n = 35). Animals were monitored for 40 weeks of life, and tumor onset was considered when a tumor reached 0.5 cm in diameter.
