Figure 2. Renal mRNA expression of Oat, Oct and Oatp transporters in cisplatin-treated mice.
Total RNA was isolated from kidneys of mice 4 days following injection with cisplatin (18 mg/kg, i.p.) or saline vehicle. RNA was analyzed by branched DNA assay for expression of Oat1-3, Oct1-3, Oatp1a1, 14, 1a6, 2a1, 2b1 and 3a1. The data are presented as mean relative mRNA expression ± SE. Asterisks (*) represent a statistical difference (p<0.05) from control.