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Anti-IL-23p19 treatment does not modulate cytokine expression in the CNS of MHV-infected mice. The temporal expression of cytokines was determined by ELISA in sham-infected and MHV-infected mice treated with either anti-IL-23p19 or control antibody. Cytokines examined include IFN-γ (A), TNF-α (B), IL-4 (C), and IL-17 (D). Data are presented as average ± SEM and represent two independent experiments with a total n = 4 for each antibody treatment group per time point examined.
