Figure 3.

PDV2 Family Members Possess a Unique C-Terminal Extension Not Found in PDV1 Family Members.

A portion of the full-length multiple sequence alignment (see Supplemental Figure 1B online) corresponding to the IMS domains of PDV1 and PDV2 is shown. The PDV2 C-terminal extension is indicated by the horizontal black bar, and the conserved C-terminal Gly of PDV2 is marked with an arrow. The outlined vertical boxed areas represent conserved residues, and the shaded boxed areas represent identical residues shared between PDV1 and PDV2 family members. For full species names of aligned sequences, see the Accession Numbers section at the end of Methods.