Table 6.
Multivariate Analysis for Overall Survival and Local-regional failure 87-04 Mitomycin-C and 92-08 No Mandatory Break Patients (n=168)
| Endpoints | Adjustment Variables | Comparison | Adjusted HR | p-value† |
|---|---|---|---|---|
| Overall Survival | Treatment | 8704 Mitomycin-C vs. 9208 No Mandatory Break | 0.57 (0.24,1.32) |
0.19 |
| Tumor Size | 2–5 vs. ≥ 5cm | 1.60 (1.04,2.46) |
0.03 | |
| Local Regional Failure | Treatment | 8704 Mitomycin-C vs. 9208 No Mandatory Break | 0.48 (0.15,1.55) |
0.22 |
| Tumor Size | 2–5 vs. ≥ 5cm | 2.68 (1.46,4.94) |
0.002 | |
†
from the Cox regression model