Fig. 1.

Early evidence for kinetochores and K fibers. a Flemming's (1882) drawing of a newt cell in anaphase of mitosis. He did not observe in his preparations that each chromosome was connected to a spindle pole by a discrete fiber. b Druner's (1895) drawing showing K fibers during anaphase in an insect spermatocyte. c Metzner's (1894) drawing depicting kinetochores during anaphase. d Hughes-Schrader's (1924) illustration of prometaphase in A.wheeleri oocytes. Note that each chromosome appears to be organizing its own minispindle within an intact nuclear envelope